in 84 days LillyDirect self-pay — Foundayo™ (orforglipron) 2.5 mg moves to $199/month See the changelog
WalletNoise

Zepbound® (tirzepatide) — 12.5 mg

Your cheapest verified route right now

verified price

$449 /month

LillyDirect self-pay

Verified Sep 29, 2026 · zepbound.lilly.com

Per year at 12 fills
$5,388
A plan exclusion is not the end. Under ACA rules you have 180 days to appeal, and secondary indications (sleep apnea for Zepbound, cardiovascular risk for Wegovy) run through different criteria. See your PBM's policy page.
Plan the whole climb, not just this month Price every fill between any two doses, over 3 to 24 months, on the dates each one actually falls. Dated price changes are already in the arithmetic. Calculate ramp cost

Every route we can price

Verified prices outrank cheaper estimates. Reference rows inform, never win.

  1. Rank 1

    LillyDirect self-pay

    $449/mo

    Rises to $699/month if the refill condition is missed.

    • Refill within 45 days to keep this price
    • Lilly's direct channel. Vial and KwikPen at identical self-pay prices at every tier. Telehealth not included.

    Verified Sep 29, 2026 · zepbound.lilly.com

  2. Rank 2

    Discount card at retail (GoodRx and similar)

    verify locally
    $299/mo
    • GoodRx sells the KwikPen presentation: its GLP-1 savings page says 'Zepbound KwikPens ... starting at $299 per month', and the Zepbound page defaults to a KwikPen prescription with a separate switch to the single-dose pen that it does not price
    • Dose- and pharmacy-dependent. Verify at your ZIP before relying on it.

    Verified Sep 8, 2026 · goodrx.com

  3. TrumpRx

    reference verify locally
    $299/mo
    • Routes you to LillyDirect, where the price varies by dose
    • Government referral site — does not sell drugs or process payments; issues coupons or routes to manufacturer DTC channels. Every figure it shows is a starting-at price — the site's own column is headed 'Lowest' — so it is a floor for the cheapest dose or intro offer, never a flat price.

    Verified Sep 16, 2026 · trumprx.gov

  4. Retail list price (reference)

    reference verify locally
    $1,087/mo
    • Cited to TrumpRx, which displays $1,087 as Zepbound's list price; drugs.com stopped publishing it and now shows the LillyDirect self-pay tiers instead
    • Context anchor only — what the drug costs with no route at all. Walk-in cash at retail typically exceeds WAC.

    Verified Sep 16, 2026 · trumprx.gov

Share or post this breakdown

Posting in r/Zepbound, r/Mounjaro, or a patient group? Copy a formatted markdown comparison with verified source citations:

Markdown Summary

Not your situation?

The same dose, priced the other ways it can be paid for. Most people arrive unsure which of these they are in — and it changes the answer more than anything else on this page.

Paying cash — uninsured, or not using insuranceCommercial plan that covers itMedicareMedicaid

Fighting a denial instead?

Coverage criteria and appeal routes, from the payers' own documents:

Aetna (CVS Health)Blue Cross Blue Shield Federal Employee Program (FEP)CVS CaremarkElevance Health / Anthem (CarelonRx)Express Scripts (Evernorth / Cigna)HumanaKaiser PermanenteMedicaid (state-by-state)Medicare (Part D + GLP-1 Bridge)Optum Rx (UnitedHealthcare)