in 84 days LillyDirect self-pay — Foundayo™ (orforglipron) 2.5 mg moves to $199/month See the changelog
WalletNoise

Zepbound® (tirzepatide) — 15 mg

Your cheapest verified route right now

verified price

$449 /month

LillyDirect self-pay

Verified Sep 29, 2026 · zepbound.lilly.com

Per year at 12 fills
$5,388
Ramp cost calculator

What the climb costs

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Both doses are yours to state, not ours to suggest. WalletNoise prices the schedule you describe and never recommends a dose, a target, or a pace — that is your prescriber's call.

12-month total $5,487 13 fills
Average per fill $422.07 peak $449
Flat at 15 mg $5,837 what multiplying today's price gives you
Climbing saves $350 lower doses cost less on the way up
Cost per fill, 2.5 mg to 15 mg
  • 2.5 mg 2×
  • 5 mg 1×
  • 7.5 mg 1×
  • 10 mg 2×
  • 12.5 mg 4×
  • 15 mg 3×
$0 $250 $500 2.5 mg — $299 Oct2.5 mg — $299 Nov5 mg — $399 Dec7.5 mg — $449 $449 Jan10 mg — $449 10 mg — $449 Feb12.5 mg — $449 Mar12.5 mg — $449 Apr12.5 mg — $449 May12.5 mg — $449 Jun15 mg — $449 Jul15 mg — $449 Aug15 mg — $449 Sep

Fills at each dose on the way up

Reset to the label minimum
  • 2.5 mg −2 +
  • 5 mg 1 +
  • 7.5 mg 1 +
  • 10 mg −2 +
  • 12.5 mg −4 +
  • 15 mg then hold

Minus stops at the label's minimum interval — this never shows a schedule faster than the manufacturer's. Staying longer on a dose is yours to choose.

Every fill, dated and priced (13)
  1. 1 Oct 9, 2026 2.5 mg LillyDirect self-pay $299
  2. 2 Nov 6, 2026 2.5 mg LillyDirect self-pay $299
  3. 3 Dec 4, 2026 5 mg LillyDirect self-pay $399
  4. 4 Jan 1, 2027 7.5 mg LillyDirect self-pay $449
  5. 5 Jan 29, 2027 10 mg LillyDirect self-pay $449
  6. 6 Feb 26, 2027 10 mg LillyDirect self-pay $449
  7. 7 Mar 26, 2027 12.5 mg LillyDirect self-pay $449
  8. 8 Apr 23, 2027 12.5 mg LillyDirect self-pay $449
  9. 9 May 21, 2027 12.5 mg LillyDirect self-pay $449
  10. 10 Jun 18, 2027 12.5 mg LillyDirect self-pay $449
  11. 11 Jul 16, 2027 15 mg LillyDirect self-pay $449
  12. 12 Aug 13, 2027 15 mg LillyDirect self-pay $449
  13. 13 Sep 10, 2027 15 mg LillyDirect self-pay $449
This is arithmetic, not a plan. Fills are spaced 28 days apart — the label's own supply length — and priced on the date each one falls, so dated price changes are already included. Your prescriber decides whether you step at all, and many people stay at a lower dose.
The label's own words (once weekly)

Initiate at 2.5 mg once weekly for 4 weeks. After 4 weeks, increase to 5 mg once weekly. The dosage may be increased in 2.5 mg increments after at least 4 weeks on the current dosage. The 2.5 mg dosage is for initiation and is not approved as a maintenance dosage. Maximum 15 mg once weekly.

Verified Sep 15, 2026 ·pi.lilly.com

Every route we can price

Verified prices outrank cheaper estimates. Reference rows inform, never win.

  1. Rank 1

    LillyDirect self-pay

    $449/mo

    Rises to $699/month if the refill condition is missed.

    • Refill within 45 days to keep this price
    • Lilly's direct channel. Vial and KwikPen at identical self-pay prices at every tier. Telehealth not included.

    Verified Sep 29, 2026 · zepbound.lilly.com

  2. Rank 2

    Discount card at retail (GoodRx and similar)

    verify locally
    $299/mo
    • GoodRx sells the KwikPen presentation: its GLP-1 savings page says 'Zepbound KwikPens ... starting at $299 per month', and the Zepbound page defaults to a KwikPen prescription with a separate switch to the single-dose pen that it does not price
    • Dose- and pharmacy-dependent. Verify at your ZIP before relying on it.

    Verified Sep 8, 2026 · goodrx.com

  3. TrumpRx

    reference verify locally
    $299/mo
    • Routes you to LillyDirect, where the price varies by dose
    • Government referral site — does not sell drugs or process payments; issues coupons or routes to manufacturer DTC channels. Every figure it shows is a starting-at price — the site's own column is headed 'Lowest' — so it is a floor for the cheapest dose or intro offer, never a flat price.

    Verified Sep 16, 2026 · trumprx.gov

  4. Retail list price (reference)

    reference verify locally
    $1,087/mo
    • Cited to TrumpRx, which displays $1,087 as Zepbound's list price; drugs.com stopped publishing it and now shows the LillyDirect self-pay tiers instead
    • Context anchor only — what the drug costs with no route at all. Walk-in cash at retail typically exceeds WAC.

    Verified Sep 16, 2026 · trumprx.gov

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Markdown Summary

Not your situation?

The same dose, priced the other ways it can be paid for. Most people arrive unsure which of these they are in — and it changes the answer more than anything else on this page.

Commercial plan that covers itCommercial plan — denied or excludedMedicareMedicaid

Fighting a denial instead?

Coverage criteria and appeal routes, from the payers' own documents:

Aetna (CVS Health)Blue Cross Blue Shield Federal Employee Program (FEP)CVS CaremarkElevance Health / Anthem (CarelonRx)Express Scripts (Evernorth / Cigna)HumanaKaiser PermanenteMedicaid (state-by-state)Medicare (Part D + GLP-1 Bridge)Optum Rx (UnitedHealthcare)