Zepbound® (tirzepatide) — 2.5 mg
- Medicaid
- Priced October 9, 2026
Your cheapest verified route right now
verified price- Per year at 12 fills
- $3,588
Medicaid coverage of GLP-1s for obesity is state-by-state (13 states as of Jan 2026). See the Medicaid policy page for the current picture and your appeal rights.
Before your next appointment: at 5 mg your cheapest route (LillyDirect self-pay) goes to $399/month — $100/month more than your current dose. WalletNoise shows the cost of a dose change, never whether to make one — that's your prescriber's call. Verified Sep 29, 2026 ·zepbound.lilly.com
Ramp cost calculator
CloseWhat the climb costs
12-month total $3,887 13 fills
Average per fill $299 peak $299
Flat at 2.5 mg $3,887 what multiplying today's price gives you
- 2.5 mg 13×
Every fill, dated and priced (13)
- 1 Oct 9, 2026 2.5 mg LillyDirect self-pay $299
- 2 Nov 6, 2026 2.5 mg LillyDirect self-pay $299
- 3 Dec 4, 2026 2.5 mg LillyDirect self-pay $299
- 4 Jan 1, 2027 2.5 mg LillyDirect self-pay $299
- 5 Jan 29, 2027 2.5 mg LillyDirect self-pay $299
- 6 Feb 26, 2027 2.5 mg LillyDirect self-pay $299
- 7 Mar 26, 2027 2.5 mg LillyDirect self-pay $299
- 8 Apr 23, 2027 2.5 mg LillyDirect self-pay $299
- 9 May 21, 2027 2.5 mg LillyDirect self-pay $299
- 10 Jun 18, 2027 2.5 mg LillyDirect self-pay $299
- 11 Jul 16, 2027 2.5 mg LillyDirect self-pay $299
- 12 Aug 13, 2027 2.5 mg LillyDirect self-pay $299
- 13 Sep 10, 2027 2.5 mg LillyDirect self-pay $299
This is arithmetic, not a plan. Fills are spaced 28 days apart — the label's own supply length — and priced on the date each one falls, so dated price changes are already included. Your prescriber decides whether you step at all, and many people stay at a lower dose.
The label's own words (once weekly)
Initiate at 2.5 mg once weekly for 4 weeks. After 4 weeks, increase to 5 mg once weekly. The dosage may be increased in 2.5 mg increments after at least 4 weeks on the current dosage. The 2.5 mg dosage is for initiation and is not approved as a maintenance dosage. Maximum 15 mg once weekly.
Verified Sep 15, 2026 ·pi.lilly.com
Every route we can price
Verified prices outrank cheaper estimates. Reference rows inform, never win.
- Rank 1
LillyDirect self-pay
$299/mo- Lilly's direct channel. Vial and KwikPen at identical self-pay prices at every tier. Telehealth not included.
Verified Sep 29, 2026 · zepbound.lilly.com
- Rank 2
Discount card at retail (GoodRx and similar)
verify locally$299/mo- GoodRx sells the KwikPen presentation: its GLP-1 savings page says 'Zepbound KwikPens ... starting at $299 per month', and the Zepbound page defaults to a KwikPen prescription with a separate switch to the single-dose pen that it does not price
- Dose- and pharmacy-dependent. Verify at your ZIP before relying on it.
Verified Sep 8, 2026 · goodrx.com
TrumpRx
reference verify locally$299/mo- Routes you to LillyDirect, where the price varies by dose
- Government referral site — does not sell drugs or process payments; issues coupons or routes to manufacturer DTC channels. Every figure it shows is a starting-at price — the site's own column is headed 'Lowest' — so it is a floor for the cheapest dose or intro offer, never a flat price.
Verified Sep 16, 2026 · trumprx.gov
Retail list price (reference)
reference verify locally$1,087/mo- Cited to TrumpRx, which displays $1,087 as Zepbound's list price; drugs.com stopped publishing it and now shows the LillyDirect self-pay tiers instead
- Context anchor only — what the drug costs with no route at all. Walk-in cash at retail typically exceeds WAC.
Verified Sep 16, 2026 · trumprx.gov
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